benigna hiperplasia prostat adalah kelainan pada prostat yang terjadi pada usia 40=60 tahun
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  BENIGN PROSTATIC HYPERPLASIA Dr. Akhtar Nawaz Orakzai FCPS Urology Institute of Kidney Diseases Hayatabad  What is BPH? ► Benign prostatic hyperplasia (BPH) is defined as a benign enlargement of the prostate gland caused by the growth of new cells ► One of the most common conditions affecting older men which can lead to LUTS ►  Advancing age and testicular androgens play a central role ►  Age related enlargement of the prostate seen in men with BPH may be caused by increased cellular proliferation combined with a decreased rate of apoptosis  Cause of BPH ► The primary androgenic stimulator of prostate growth is dihydrotestosterone (DHT) ► DHT is produced from testosterone via the 5alpha-reductase (5AR) isoenzymes type I and II
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