of 36
All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
Related Documents
  Amino Acid Catabolism: N  Copyright © 1999-2008 by Joyce J. Diwan. All rights reserved. Molecular Biochemistry II  There are multiple transaminase enzymes which vary in   substrate specificity . Some show preference for particular amino acids  or classes of amino acids as amino group donors, and/or for  particular -keto acid acceptors . H R 1  C COO -  + R 2 C COO -  NH 3+  O Transaminase H R 1  C COO -  + R 2 C COO -  O NH 3+ Transaminases  (aminotransferases) catalyze the reversible reaction at right.  Example of a Transaminase  reaction:  Aspartate donates its amino group, becoming the a -keto acid oxaloacetate.   a -Ketoglutarate accepts the amino group,  becoming the amino acid glutamate. aspartate a -ketoglutarate oxaloacetate glutamate Aminotransferase (Transaminase) COO  CH 2 CH 2 CCOO  OCOO  CH 2 HCCOO  NH 3+ COO  CH 2 CH 2 HCCOO  NH 3+ COO  CH 2 CCOO  O + +  In another example, alanine becomes pyruvate as the amino group is transferred to a -ketoglutarate. alanine a -ketoglutarate pyruvate glutamate Aminotransferase (Transaminase) COO  CH 2 CH 2 CCOO  OCH 3 HCCOO  NH 3+ COO  CH 2 CH 2 HCCOO  NH 3+ CH 3 CCOO  O + +
We Need Your Support
Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

Thanks to everyone for your continued support.

No, Thanks