Business

EJC -Uterine pinopodes in spontaneous and artificial cycles: relationship to implantation window (IW) Search for in Any Field in This Journal

Description
The implantation window (IW) may be altered under different conditions. In oocyte donation (OD), where manipulation of hormones is possible implantation rates (IR), are higher. Pinopodes are protrusions of the apical surfaces of the uterine luminal
Categories
Published
of 2
All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
Related Documents
Share
Transcript
  EJC - Uterine pinopodes in spontaneous and artificial cycles: relationship to implantation window (IW).http://journals.ohiolink.edu/ejc/article.cgi?issn=10715576&issue=v03i0002&article=185a_upisaacrtiw[2/7/2013 12:16:11 PM] ◄  | ► Format/export as:  APA   E-Mail This Article Export to RefworksExport to ReferenceManager Login or Create an Account. EJC Home. Search for in  Any Field  in This Journal   More Like ThisJournal of the Society for Gynecologic Investigation, Volume 3, issue 2 (March 4, 1996), p. 185A ISSN: 1071-5576Elsevier Science[ PDF Full Text] Uterine pinopodes in spontaneous and artificialcycles: relationship to implantation window (IW). Background: The implantation window (IW) may be altered under different conditions. In oocyte donation(OD), where manipulation of hormones is possible implantation rates (IR), are higher. Pinopodes areprotrusions of the apical surfaces of the uterine luminal epithelium, reported by Psychoyos and Nikas(Asst. Reprod Rev 4:26-32, 1994) to appear on Cycle Day (D), 19-20 in spontaneous cycles, (SC). The aim of this study was to investigate whether the pinopodes can serve as markers for the IW (D 19-21) anddetermine possible differences between spontaneous vs. artificial cycles, (AC), of patients undergoing OD.Methods: Endometrial biopsies (EB x ) were obtained from 13 oocyte recipients twice during Mock cycles onD 20 and D 26. They received Estrace 2, 4, 6 mg/d as of D 1-7, 8-11, 12-14, and on D 15 started 50 mgprogesterone. Sixteen SC infertile women were also evaluated and had EBx on D 20 (LH+6) and D 26(LH+12). The EB x  were obtained by Pipelle (Prodimed, France) A portion was fixed in 2.5% glutaraldehydein 0.1 phosphate buffer for Electon Microscopy (EM) and the rest for histological study to evaluateendometrium for being in or out of phase, (Noyes Criteria)Results:On D 20 pinopodes are present in 75% of SC and only 25% of AC. By histologic evaluation 25% of SC are inphase while none of AC. These data can be interpreted as suggesting a delay in the IW which may be thereason for higher implantation rates in AC of oocyte donors. Conclusion: The data support the idea thatMaroulis, G.B.; Zarmakoupis, P.N.; Nicosia, S.V.; Yeko, T.R.; Mayer, J.C.; Haller, E.; O'Brien, W.F. OL Home | EJC HomeSearch | Contact a Librarian   APA Go Any FieldThis Journal Go  EJC - Uterine pinopodes in spontaneous and artificial cycles: relationship to implantation window (IW).http://journals.ohiolink.edu/ejc/article.cgi?issn=10715576&issue=v03i0002&article=185a_upisaacrtiw[2/7/2013 12:16:11 PM] pinopodes may be markers of IW since they appear on D 20 in most SC. The results suggest that IW maybe chronologically shifted possibly accounting for higher pregnancy rates in OD where AC are used. Keywords:
Search
Similar documents
View more...
Tags
Related Search
We Need Your Support
Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

Thanks to everyone for your continued support.

No, Thanks