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1. HOW SYNAPSES WORKS WITH DRUGS D2 AND 5-HT systems are involved in drug misuse and addiction (pleasure and feel good factor) 1.Drugs block receptors so…
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  • 1. HOW SYNAPSES WORKS WITH DRUGS D2 AND 5-HT systems are involved in drug misuse and addiction (pleasure and feel good factor) 1.Drugs block receptors so neurotransmitters can’t fit into them • This reduces nerve impulses (Antagonists) 2. Drugs attach to the receptors and act the same as the neurotransmitter • Increases nerve impulses (Agonists) 3. Drugs prevent recycling (reuptake) of neurotransmitter • Mimic neurotransmitters and prevent re-uptake (SSRI) so they can stay longer in the synapse AGONIST An apparent sensory experience that arises in the absence of an external stimulus ANTAGONIST Increase the probability of nerve impulses Blocks neurotransmitter effects EXCITORY Drugs which increase the frequency of nerve impulses INHIBITORY STIMULANTS A drug that induces calmness or sleep DEPRESSANTS Drugs which decrease the frequency of nerve impulses SEDATIVE Decrease the probability of nerve impulses HALLUCINATION Mimics the effect of neurotransmitter OPIATE A drug from a group that contains morphine and heroin. Original source was the opium poppy. 1. According to scientists, what is the master molecule of addiction and where is it produced? [2] 2. Describe the mode of action at the synapses of a drug [4]
  • 2. ANSWERS - HOW SYNAPSES WORKS WITH DRUGS D2 AND 5-HT systems are involved in drug misuse and addiction (pleasure and feel good factor) 1.Drugs block receptors so neurotransmitters can’t fit into them • This reduces nerve impulses (Antagonists) 2. Drugs attach to the receptors and act the same as the neurotransmitter • Increases nerve impulses (Agonists) 3. Drugs prevent recycling (reuptake) of neurotransmitter • Mimic neurotransmitters and prevent re-uptake (SSRI) so they can stay longer in the synapse AGONIST Mimics the effect of neurotransmitter Blocks neurotransmitter effects ANTAGONIST Increase the probability of nerve impulses Decrease the probability of nerve impulses EXCITORY INHIBITORY STIMULANTS Drugs which increase the frequency of nerve impulses DEPRESSANTS Drugs which decrease the frequency of nerve impulses SEDATIVE A drug that induces calmness or sleep HALLUCINATION An apparent sensory experience that arises in the absence of an external stimulus OPIATE A drug from a group that contains morphine and heroin. Original source was the opium poppy. 1. According to scientists, what is the master molecule of addiction and where is it produced? [2] D2 is thought to be the master molecule of addiction It is made in the brain and affects primitive parts of the brain 2. Describe the mode of action at the synapses of a drug [4]
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