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NIS and special vaccines
  ã Immuno-biological substance designed to produce specific protection against a given disease. ã Stimulates the production of protective antibodies and other immune mechanisms. ã Types; ã Live vaccines ã Inactivated or killed vaccines ã Toxoids ã Cellular fractions ã Combinations   Prepared from live organisms. (Generally attenuated)  Passed repeatedly in lab and have lost capacity to induce full blown disease.  Contraindicated in:  Immune deficiency diseases  Suppressed immune response e.g. leukemia, lymphomas, chemotherapy etc.   Organisms killed by heat or chemicals.  Usually administered by subcutaneous or intramuscular route.  Usually require a primary series of doses and then boosters.
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