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CEFALOSPORINAS

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CEFALOSPORINAS
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  CEFALOSPORINAS TM ALEJANDRA SOTO LABRA  ESTRUCTURA NUCLEO CEFEMVENTAJAS RESISTENTES A PENICILINASAS Cambio en el metabolismoy propiedadesfarmacocinéticasde la droga Cambioen actividadantibacteriana  CEFALOSPORINAS Primera GeneraciónSegunda GeneraciónTercera GeneraciónCuarta GeneraciónCefalexinaCefalotinaCefradina Cefazolina CefadroxiloCefaclorCefoxitin Cefuroxima CefprozilCefotaximaCeftazidimaCeftriazonaCefoperazonaCefiximeCefepimeCefpiromeQuinta GeneraciónCeftarolinaCeftobiprol  Antibiótico Administración Espectro actividad Indicaciones mas importantes Cefalexina OralCocos grampositivos yalgunos bacilosgramnegativos de lacomunidad •  Infecciones de piel ytejidos blandos( impétigo,forúnculos, celulitis)   Faringitis  Streptocócicas (alternativa)Cefazolina Parenteral(IM; IV)Profilaxis quirúrgica Aplicaciones cefalosporinas
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